According to the Cancer Prevention and Treatment Fund, “for every four diagnoses of invasive breast cancer in the United States, there is one diagnosis of DCIS. The growing incidence of DCIS is a direct result of higher mammography screening rates. In 2008, the age-adjusted incidence rate of DCIS was 32.5/100,000 women. Incidence is highest in women age 50-64 at approximately 88/100,000 women.”
DCIS according to this DCCC Cancer Consortium is “rarely diagnosed in women younger than 40. Risk increases steadily from age 40 to 50 years, more slowly after 50, and plateaus after age 60. As with invasive cancer, risk factors include high mammographic breast density, family history of breast cancer, increasing age (until age 70), use of combination hormone therapy for menopause (estrogen with progestin), late age at menopause, nulliparity (no births), late age at first birth, and high postmenopausal BMI.”
“The most common histological subtype is the less-aggressive “noncomedo.”
What I found interesting was that the MRI was more sensitive to detecting multicentric DCIS. I personally had that experience whereas it didn’t show up on the mammogram. Then again the ultra sound was done on half a breast by a technican doing half of her job.
Whose at high risk for a recurrence? According to this fact sheet presented by the DC Cancer Consortium through the Department of Health, Government of the District of Columbia, “Younger patients with symptomatic presentation (palpable), and black patients are at higher risk.” “Some characteristics are also associated with local recurrence and progression to invasive cancer, including high grade, “comdo-type” necrosis, large size, and extensive distribution.” (I personally think this is important since I was misdiagnosed initially on the stage and the type by the pathologist. What also happens is the oncologist goes back to the initial diagnosis. I had three surgeries for this cancer. Should I have gone to the Mayo Clinic it would of been done in one surgical procedure? I think I should of. After 3 surgeries you have substantial scar tissue and pain.)
I also have found out that there are different end points from the State-of-the Science Conference: The Latest Research. A study was published in the Journal of the National Cancer Institute (2011) on the long-term outcomes of DCIS patients. It involved 813 patients in the B-17 trial and 1799 patients in the B-24 trial. The B-17 compared lumpectomy with lumpectomy only and then the other was a lumpectomy with radiation. The B-24 trial compared a placebo with L+R and compared it to L+R and tamoxifen +TAM.
Fast Facts on DCIS-I have one copy but am willing to copy it for you, unless it is downloadable on the site.
DCIS-We have limited copies of the booklet on this topic, should you be interested, contact: firstname.lastname@example.org